Cosmo Companion™ with Methylfolate – Alcohol Defense


Alcohol consumption blocks an enzyme called MTHFR that converts folate into its active form, methylfolate. Methylfolate repairs damaged DNA when it mutates, and is a critical component for the health of every cell in your body. Drinking alcohol can deplete methylfolate to critically low levels, especially since up to 50% of the population carry an MTHFR gene mutation or variation that makes this important enzyme work inefficiently. Cosmo Companion not only contains the bioactive form of methylfolate – so you replenish what alcohol takes away – it also contains 15 potent botanicals to support and protect the liver as it detoxifies alcohol while promoting improved alcohol sugar metabolism. Our unique formulation makes Cosmo Companion the most effective supplement to arm yourself against the negative effects of drinking alcohol.

  • For casual drinkers and those who consume alcohol regularly.
  • Excellent solution for anyone with an MTHFR gene mutation or variation.
  • Contains bioactive methylfolate to support cellular health and proper cell regeneration.
  • Reduces alcohol-induced nutrient deficiency.
  • Supports liver function and detoxification.
  • Supports alcohol metabolism and glucose stability.
  • Comes packed with 15 other essential ingredients.
  • Free of estrogen & hormones. Vegan, Non-GMO, Soy-Free & Gluten-Free.
  • Also available via discounted auto ship subscription.

Existing customers: This is our NEW 1-month supply bottle

1-Month Supply
30 Tablets
Exclusively from Pink Lotus Elements

In stock

glamour magazine logo

“Whether you are a casual drinker or enjoy that glass of wine every evening after work, Cosmo Companion is a truly innovative and science-backed way to combat the negative effects of alcohol consumption”
-Glamour Magazine

rachael ray show logo

“This “Alcohol Defense” Supplement Could Help Minimize The Negative Impact Of Too Many Drinks”
-Rachael Ray Show

entrepreneur magazine logo

“For the millions of women (and men) who enjoy a regular drink, Cosmo Companion delivers a comprehensive methylfolate formulation that protects against the negative health effects of alcohol”

elephant journal logo

“The peace of mind of knowing you are doing everything you can to support your health and well-being, whilst still being able to enjoy a drink…and moderate levels of sanity during lockdown”
-Elephant Journal

maxim magazine logo

“Other bestsellers in their lineup, like their Multi Must Have or Cosmo Companion, deliver scientifically-backed results for the general women’s health and wellness communities”

Below are some of the most frequently asked questions we receive from our customers about Cosmo Companion. Please let us know of any questions that we should add. You can let us know by clicking on the chat icon in the bottom right corner of your screen.

Is Cosmo Companion only for women?

No. As much as we are a women’s health brand, Cosmo Companion is 100% suitable for men as well.

What kind of results will I see and how quickly?

You will not notice a physical difference, but the results from Cosmo Companion are instant upon taking the supplement. It’s much like giving your car an oil change. It won’t drive any better, but you know the engine won’t break down. Once you ingest the ingredients, your body will know precisely what to do with them, and since they are provided in their bioactive form, Cosmo Companion is metabolism-ready! This is important since standard B vitamins (found in so many over-the-counter cheap Multivitamins) require energy intensive conversion to their bioactive form. Many people also lack the ability, either due to genetics or an overloaded liver, to ever convert standard nutrients into bioactive forms. Cosmo Companion bypasses this problem due to our selection of only the most high-end, non-synthetic and bioactive ingredients.

Will Cosmo Companion help me get rid of bad hangovers?

As a general rule, Cosmo Companion is not a hangover supplement. The goal of our formulation is to help mitigate the negative health effects of alcohol and to support cellular health and correct regeneration, which is something that happens inside your body without you ever noticing it. However, our powerhouse list of ingredients do limit alcohol induced nutrient deficiency, support liver function and detoxification and also support alcohol metabolism and glucose stability. This means that you may see slight improvements compared to not taking the product when experiencing a hangover. Having said that, if you drank so much the night before that you are actually experiencing a serious hangover, you will experience it one way or another. Cosmo Companion still provides all of its health benefits, but you should not expect to feel any better as a result.

Can’t I just take more of my folic acid supplement instead?

Unfortunately, no. MTHFR, the enzyme responsible for turning Folic Acid into methylfolate, is temporarily disabled by alcohol, decreasing folate absorption from the intestines and increasing its excretion in the kidneys, which basically means your Folic Acid supplement isn’t much more than a waste of money. Overloading on Folic Acid will not accomplish desirable results for alcohol consumers, which is why Cosmo Companion contains the bioactive, non-synthetic and metabolism-ready form of methylfolate and 15 other powerhouse ingredients to provide the best defense and support your health.

Do I only take the product on days when I drink?

Our most frequently asked question, for sure. Here are 2 things you need to know:

First, if you have an MTHFR variation or mutation, your body’s natural ability to convert Folic Acid into Methylfolate is limited, which means you likely have a folate deficiency regardless of whether you drink alcohol or not. If you fall into this category, it is advised that you consume the recommended dose, 1 tablet per day. How do you know if you have an MTHFR variation or mutation? You wouldn’t unless you tested for it. However, it is estimated that almost half of Americans have one, so the odds are certainly high. Having an MTHFR gene variation is basically like having a typo in the gene that tells the enzyme how to function. The enzyme will still work, but its activity is compromised to only provide 65% to as little as 30% of its normal function. MTHFR variations are especially common among Hispanics, Caucasians and Asians.

Second, your diet plays a major role. Each person has different levels of Methylfolate in their body, primarily a result of how good or bad the diet is. Folate is found in nuts, spinach, collard greens, asparagus, peas, beans and fortified whole wheat sources. However, heat destroys it, which means that folate food sources like these have to be eaten raw to have any positive effect. With that in mind, a standard American diet would not provide anywhere near the amount of folate-rich foods required. So it may come as no surprise that folate deficiency is the most common vitamin deficiency in the world. So, if you are on a standard diet that does not include frequent intake of these raw foods, it is advised that you consume the recommended dose, 1 tablet per day. However, if you have significant and regular intake of these folate-rich foods and are not one of the 50% of Americans with an MTHFR gene malfunction, then taking the product only on days where you drink will work just fine. If this is you, try taking the product before you have a sip. If you forget, that’s fine as well, just make sure to take it as soon as possible afterwards.

Should I still take my folic acid supplement?

No. If you take Cosmo Companion daily, there is no need to take your folic acid supplement. If you are pregnant, however, your physician may advise you to increase your intake of folic acid – this is fairly common practice. Depending on the recommended dose by your physician, you may end up taking more than 1 tablet per day, or use a folic acid supplement in addition to taking Cosmo Companion.

Where do I keep my Cosmo Companion bottle?

We recommend that you store your bottle in a cool and dry place like a kitchen cabinet. Putting your Cosmo Companion tablets in a pill container will work fine as well. Just make sure to keep it away from sunlight and humidity.

Do you offer a subscription for the product?

Yes, you can have Cosmo Companion delivered at a discount via our Semi Monthly Auto Ship Subscription.

Do you still offer the 2-month supply bottle you used to have?

No, we changed Cosmo Companion to a 1-month supply product to make it easier for our subscription customers to bundle the product with their other subscriptions.

  • Supplement Facts

  • Servings Per Container30
  • Serving Size1 Tablet
  • Amount per serving
  • Calories0
  • % Daily Value*
  • Vitamin A (as retinyl palmitate)750 mcg (2500 IU)83.45%
  • Vitamin C (as ascorbic acid)40 mg44%
  • Vitamin B1 (as benfotiamine)1.5 mg125%
  • Vitamin B2 (as riboflavin 5' phosphate sodium)1.7 mg131%
  • Niacin (as inositol hexanicotinate)20 mg125%
  • Vitamin B6 (as pyridoxal-5-phosphate monohydrate)2 mg118%
  • Folate (as Calcium L-5-Methyltetrahydrofolic [5-MTHF]) (Magnafolate®C)800 mcg DFE (470mcg folic acid)200%
  • Vitamin B12 (as methylcobalamin)60 mcg2500%
  • Biotin300 mcg1000%
  • Vitamin B5 (as Pantethine)10 mg200%
  • Calcium (from Red algae calcium carbonate [Aquamin®])50 mg4%
  • Chromium (from Chromium complex [Crominex® 3+])60 mcg171%
  • Turmeric (Curcuma longa) root extract150 mg
  • Milk thistle (Silybum marianum (L.) Gaetn.) seed extract100 mg
  • Glutathione (Setria®)50 mg
  • Artichoke (Cynara scolymus) leaf extract50 mg
SKU: PLE17-NTC-6324
Brand: Pink Lotus Elements
Category: Ever After, Supplements
Weight: 0.2 lbs
Dimensions: 2 × 2 × 4 in
Size: 150cc
Count per Bottle: 30
Suggested Use: Take 1 tablet daily, preferably with a meal
Supplement Type: Tablet
Supply For: 1 Month

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We are a trusted women’s health brand since 2007

Customer Reviews
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Angelo E.

Pint Lotus

Quality was great

Megan H.

Love the peace of mind

I have taken this since being in remission of colon cancer. I love knowing if I drink alcohol that Cosmo Companion helps process the alcohol more safely.

pat m.

Great stuff

Love this product - just wish I could get more content in each container - 30 tabs in a container that will hold at least 90 seems wasteful We do have environmental issues

Elaine T.

Cosmo Companion

Easy to take . I drink socially and I felt fine after a couple of drinks. Also taking Tomoxifin and didn’t have any hangover feeling.


Big fan

After my breast cancer last year I have maintained a very healthy diet and active lifestyle. I decreased my alcohol consumption and have about 3-4 drinks a week.. I take Cosmo Companion right before I have a drink. The next day I wake up with energy, clear headed and little of the morning after depression I would get before. Highly recommend this product!